Wednesday, June 29, 2022 Daily Archives

CDMO plant roundups: News from CRL, Batavia, OrganaBio

Charles River opens a plasmid DNA plant in the UK, Batavia Biosciences is building a commercial vaccine facility in the Netherlands, and OrganaBio’s cell therapy manufacturing site in Florida is now up and running. Welcome to our CDMO roundup. First up this week is Charles River Laboratories (CRL), which – fresh from bagging contracts with Ziphius Vaccines and ASC Therapeutics – has opened its High Quality (HQ) Plasmid DNA Centre of Excellence at Bruntwood SciTech’s Alderley Park in Cheshire, United…

Astellas turns to next-gen ADCs with $90m Sutro partnership

Astellas will codevelop immunostimulatory antibody-drug conjugates (iADCs) for three biological targets through a partnership with Sutro Biopharma. Japanese biopharma firm Astellas will pay Californian biotech Sutro $90 million but could pay a further $422.5 million in development, regulatory and commercial milestones for each of the three undisclosed oncology candidates. While antibody-drug conjugates (ADCs) have established themselves on the commercial front, with 12 approved in the US, Sutro says its engineered iADCs are a potential groundbreaking modality in the treatment of…