Vertex will bolster its inhouse manufacturing capabilities while adding three cell therapy approaches to type 1 diabetes through the acquisition of ViaCyte. In 2019, Vertex Pharmaceuticals entered the diabetes cell therapy space through the $950 million acquisition of Semma Therapeutics. The deal brought Vertex a stem cell-derived islet platform and VX-880, an allogeneic candidate for type 1 diabetes (T1D), entering the firm into the relatively small islet cell space. Now the firm plans to remove its main competition, ViaCyte, through…
Tuesday, July 12, 2022 Daily Archives
ABL and KaliVir collaborate to advance oncolytic viruses
ABL will provide materials and manufacture KaliVir Therapeutics’ oncolytic viruses for its forthcoming clinical trial. Financial details of the partnership have not been disclosed but contract development manufacturing organization (CDMO) ABL will produce KaliVir’s oncolytic viruses and provide the material required to perform its first-in-human- clinical study with oncolytic vaccinia virus. The oncolytic vaccinia virus is derived from KaliVir’s VET platform, which has been optimized for systemic delivery as well as expression of therapeutic transgene in the tumor. Furthermore, the…