Thursday, September 15, 2022 Daily Archives

Forge Bio bags $90m funding to expand CGT capabilities

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CDMO Forge Biologics has completed a $90 million Series C financing round, which will be used to expand its technologies, manufacturing systems, and cell lines. The gene therapy contract development manufacturing organization (CDMO) Forge Bio has raised $90 million with finances led by Aisling Capital, Drive Capital, and an undisclosed strategic investor. According to the CDMO, it will expand the number of its service offerings available to customers in order to scale its gene therapy programs from research to clinical…

September 15, 2022

Biden pledges $2bn to launch US biomanufacturing initiative

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The US government will invest over $2 billion to launch its biomanufacturing initiative, which aims to expand manufacturing capacity in the country and ensure pandemic preparedness. The Executive Order was signed by President Biden on Monday and outlines the key goals of the biomanufacturing initiative. Overall, the Order looks to strengthen the country’s supply chain in the biopharma space and to reduce reliance on foreign manufacturing for the drug industry. Biden said it is the policy of his Administration to…

September 15, 2022

Novel Dual-Plasmid Transfection System Improves Titer And Product Quality In AAV Manufacturing

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Adeno-associated virus (AAV) vectors are a widely-used, versatile, and appealing gene therapy delivery platform because of their high safety profile and ability to target many different cell types and transport healthy gene copies into a patient’s cells. The recent clinical successes of AAV-mediated gene therapies have ignited much interest in solutions for the scalable, good manufacturing practice (GMP) production of AAVs, and high demand for outsourced development and manufacturing capabilities. Yet, significant challenges remain, particularly around product quality, productivity, and…

September 15, 2022