Friday, October 14, 2022 Daily Archives

Improving Titer, Quality and Efficiency of AAV Manufacturing and Production by Optimizing Osmolality

The rate of innovation within Cell and Gene Therapy is incredible and will continue to grow at an exponential rate as new methodologies are developed. With the novel techniques, come new and improved manufacturing procedures for sought after therapies. The use of viral vectors is now a common approach within the sector, but there are still difficulties when scaling up for bioprocessing. An example being a recovery range of 5-30%, a less than optimal result within the manufacturing process. When…

Inceptor and Avectas team to improve CAR-T manufacturing

The collaboration between Inceptor Bio and Avectas will aim to improve the development and production of CAR-T cell therapies for the treatment of solid tumors. Financial details and length of the partnership remain under wraps. However, under the terms of the agreement, Inceptor will use Avectas’ Solupore technology as a substitute to electroporation for engineering T cells with the aim to produce an improved T cell product. In April 2021, Avectas received $8.7 million in funding to develop the cell…