Therapeutic Modalities

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Bioprocess Insider

Biomanufacturing in space accelerating therapy development on Earth Biomanufacturing in space accelerating therapy development on Earth

The International Space Station (ISS) is hosting a live webinar on Friday, 26 July that will discuss upcoming scientific investigations that are launching on Northrop Grumman's 21st Commercial Resupply Services mission. Speakers will discuss life science applications such as biomanufacturing in space.

byJosh Abbott, Editor, BioProcess Insider

Jul 24, 2024

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1 Min Read

Analytical Considerations for Gene-Modified Hematopoietic Stem and Progenitor Cell Therapies: Part 2 — Starting Materials and Drug Substances Analytical Considerations for Gene-Modified Hematopoietic Stem and Progenitor Cell Therapies: Part 2 — Starting Materials and Drug Substances

byBrent Morse, Alicja Fiedorowicz

Jun 19, 2024

Elevating the CGT Manufacturing Game: How Outsourcing Enables Success Elevating the CGT Manufacturing Game: How Outsourcing Enables Success

byOmkar Kawalekar, Audrey Greenbergand 1 more

Jun 12, 2024

BPI ATE Recap Logo

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Moving Towards Scalable AAV Vector Production with High Volumetric Efficiency (Webcast Recap)Moving Towards Scalable AAV Vector Production with High Volumetric Efficiency (Webcast Recap)

byPrasanna Srinivasan, Graziella Piras

Jun 12, 2024

Allogeneic Cell Therapy eBook cover

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eBook: Allogeneic Cell Therapy — From Clinical Concept to Viable Product eBook: Allogeneic Cell Therapy — From Clinical Concept to Viable Product

byDiane McCarthy, Brian Gazailleand 5 more

May 31, 2024

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High Aggregate Levels with Engineered Monoclonal Antibodies: An Innovative Approach to Addressing the Challenge High Aggregate Levels with Engineered Monoclonal Antibodies: An Innovative Approach to Addressing the Challenge

byYing Chen, Al de Leon

May 14, 2024

Analytical Considerations for Gene-Modified Hematopoietic Stem and Progenitor Cell Therapies: Part 1 — In-Process and Drug Product Control

Analytical Considerations for Gene-Modified Hematopoietic Stem and Progenitor Cell Therapies: Part 1 — In-Process and Drug Product Control

byBrent Morse, Alicja Fiedorowicz

Bringing Your Cell and Gene Therapy Offerings to Market

Bringing Your Cell and Gene Therapy Offerings to Market

Monoclonal Antibody Productivity

A Fully Single-Use Downstream Process for Monoclonal Antibodies

A Fully Single-Use Downstream Process for Monoclonal Antibodies

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byShunsuke Shiina, Neha Saxenaand 1 more

Sino Biological’s Center for Bioprocessing (C4B) in Houston, TX

Emerging Therapeutics

Recombinant Antibody Technology: Its Criticality to Past and Future Biopharmaceutical Success

Recombinant Antibody Technology: Its Criticality to Past and Future Biopharmaceutical Success

bySuranjana Sen

Characterization methodologies

Emerging Therapeutics

Intact and Subunit Molecular Mass Analysis for Development of Antibody Therapeutics: Considerations for Novel Biotherapeutics and Biosimilars

Intact and Subunit Molecular Mass Analysis for Development of Antibody Therapeutics: Considerations for Novel Biotherapeutics and Biosimilars

bySanjib Banerjee, Rajiv Bharadwaj

Artificial intelligence

Information Technology

Using Artificial Intelligence for Monoclonal Antibody Discovery

Using Artificial Intelligence for Monoclonal Antibody Discovery

byWilliam Whitford

Therapeutic Modalities

Clean room worker using a computer

Emerging Therapeutics

The Evolution of Medicine: Empowering Healthcare for the Delivery of Advanced Therapies

The Evolution of Medicine: Empowering Healthcare for the Delivery of Advanced Therapies

byRohin Iyer, Robert Brackner

blue and purple mass of cells

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Setting the Standard in Cell- and Gene-Therapy Manufacturing: Tackling Performance, Scalability, and Regulatory Compliance Challenges Together

Setting the Standard in Cell- and Gene-Therapy Manufacturing: Tackling Performance, Scalability, and Regulatory Compliance Challenges Together

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byPrity Bengani-Lutz, Lorraine Borlandand 4 more

Biomanufacturing scientists

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Biologics Manufacturing from Gene to Product

Biologics Manufacturing from Gene to Product

byThilo Kamphausen, Kai Pohlmeyer

Macroscopic macrophage image

Emerging Therapeutics

A Milestone in Macrophage-Based Cancer Treatment: Leveraging Chimeric Antigen Receptors To Address Solid Tumors

A Milestone in Macrophage-Based Cancer Treatment: Leveraging Chimeric Antigen Receptors To Address Solid Tumors

byBrian Gazaille, Michael Klichinsky

hydrogels as cell encapsulants

Characterization of Hydrogel Carriers: Improving the Efficacy of Existing Cell Therapies

Characterization of Hydrogel Carriers: Improving the Efficacy of Existing Cell Therapies

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byStella Vnook, Megan Hamiltonand 1 more

Blue cells

Derisking the Road to Commercially Viable Stem-Cell Therapies

Derisking the Road to Commercially Viable Stem-Cell Therapies

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byRicardo Baptista, Stijn Heessenand 2 more

integration of four deterministic lateral displacement (DLD) sorting arrays in parallel on a single chip

Microfluidic Cell Sorting: Scaling for Clinical and Therapeutic Applications

Microfluidic Cell Sorting: Scaling for Clinical and Therapeutic Applications

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byNicholas Tan Kwan Zen, Jongyoon Hanand 1 more

CAR-T Therapy Manufacturing: Lessons from the Automotive Industry

CAR-T Therapy Manufacturing: Lessons from the Automotive Industry

heart tissue cells

Regenerative Medicine for Cardiovascular Disease: Characterization and Clinical Success

Regenerative Medicine for Cardiovascular Disease: Characterization and Clinical Success

byIbon Garitaonandia

Mirus RevIT AAV enhancer

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Rev Up AAV Genome Production

Rev Up AAV Genome Production

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byBecky Reese, Jennifer Swansonand 2 more

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Vaccine Downstream Production: Purification Tools for Various Modalities

Vaccine Downstream Production: Purification Tools for Various Modalities

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byDavid Humphries, Sirat Sikkaand 4 more

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eBook: Heralding mRNA and NRTIs — Perspectives on Drug Invention and Development

eBook: Heralding mRNA and NRTIs — Perspectives on Drug Invention and Development

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byBrian Gazaille, Joseph P. Allenand 2 more

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eBook: Next-Generation Gene Therapies and AAV Products

eBook: Next-Generation Gene Therapies and AAV Products

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byDan Stanton, Shreeyashi Ojhaand 1 more

Developing Protein-Based Vaccines for SARS-CoV-2

Developing Protein-Based Vaccines for SARS-CoV-2

Technological innovation is energizing the vaccine industry

Introduction: Prologue to a Postpandemic Future

Introduction: Prologue to a Postpandemic Future

“Long COVID” Pandemic Continues To Reshape the Vaccine Sector

“Long COVID” Pandemic Continues To Reshape the Vaccine Sector

byGareth Macdonald

Improving Immune Responses To Treat Breast Cancer Strategies for Developing Therapeutic Cancer Vaccines

Improving Immune Responses To Treat Breast Cancer Strategies for Developing Therapeutic Cancer Vaccines

byBrian Gazaille, William V. Williams

Multiserotype Glycoconjugate Vaccines: Investigation into Membrane Fouling Behavior on Sterility Filters

Multiserotype Glycoconjugate Vaccines: Investigation into Membrane Fouling Behavior on Sterility Filters

byJosh Abbott, Zhuoshi Du

Comparability for Cell and Gene Therapy Products: A Challenge and an Opportunity

Comparability for Cell and Gene Therapy Products: A Challenge and an Opportunity

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byK.R. Poudel, Zenobia Taraporewalaand 3 more

eBook: ADC Advances — Leveraging Classical and Emerging Technologies

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eBook: ADC Advances — Leveraging Classical and Emerging Technologies

eBook: ADC Advances — Leveraging Classical and Emerging Technologies

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byBrian Gazaille, David Dornanand 1 more

Getting Cell Therapy Right at the Source

Getting Cell Therapy Right at the Source

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Navigating GMP Manufacturing of mRNA-Lipid Nanoparticles

Navigating GMP Manufacturing of mRNA-Lipid Nanoparticles

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byAngela Johnson, Laura Hoand 1 more